COORDINATION BEHAVIOUR OF DEPENDENT pH PYRAZINE DERIVATIVES
Author(s):
Shailesh Kumar
Keywords:
anti-tumour, antibiotic and diuretic etc.
Abstract
Pyrazine is a symmetrical molecule belonging to D2h point Group. It is less basic than pyridine, pyridazine and pyrimidine. Derivatives such as Phenazine are well known for their antitumour, antibiotic and diuretic activities. Tetramethyl pyrazine, also known as ligustrazine, is reported to scavenge superoxide anion and decrease nitric oxide production in human polymorphonuclear leukocytes and is a component of some herbs in traditional Chinese medicine. Alkylpyrazines are chemical compounds based on pyrazine with different substitution patterns. Some alkylpyrazines are naturally occurring highly aromatic substances which often have a very low odour threshold and contribute to the taste and aroma of various foods including coffee and wines. Alkylpyrazines are also formed during the cooking of some foods via Maillard reactions. 2,3-Dimethylpyrazine is a component of the aroma of roasted sesame seeds.
Article Details
Unique Paper ID: 157162
Publication Volume & Issue: Volume 7, Issue 1
Page(s): 1085 - 1087
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