FORMULATION OF TOPICAL GEL CONTAINING CYMBOPOGON CITRATUS OIL & EVALUATION OF ITS ANTIMICROBIAL ACTIVITY

FORMULATION OF TOPICAL GEL CONTAINING CYMBOPOGON CITRATUS OIL & EVALUATION OF ITS ANTIMICROBIAL ACTIVITY
Author(s):
R. D. Motghare, A. O. Maske, A. D. Wanjari, S.S. Gupta, R. B. Agarawal
Keywords:
Cymbopogon citratus oil, antimicrobial activity, carbopol 934
Abstract
Since ancient era, herbal- or plant-based medicines has been used for the prevention, cure & mitigation of diseases. The volatile oil obtained from the fresh leaves of the plant is one of the most important essential oils in the food, cosmetics, and pharmaceutical industries. Considering these advantages, herbal gel containing Cymbopogon citratus oil was prepared. Solvent extraction method was used for extraction of essential oils. After extraction, some of physicochemical properties of the extract were determined .Then topical gel was prepared by taking carbopol 934 ,triethanolamine methyl and propyl paraben ,propylene glycol and three different measured amount of Cymbopogon citratus oil was incorporated to gel and labeled as F1,F2 and F3 and evaluated for physical parameters and in-vitro antimicrobial activity against E.coli. The formulation F3 shows best formulation for antimicrobial activity than F1 and F2.
Article Details
Unique Paper ID: 153475 Publication Volume & Issue: Volume 8, Issue 7 Page(s): 584 - 588
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