Sickle cell anemia

Sickle cell anemia
Author(s):
Abhishek.P.Suryawanshi, Lad G.S, Nandkishor B Bawage, Dr. Shaymlila B Bawage
Keywords:

Abstract
This paper reviews Sickle cell anemia. Sickle cell anemia is a homozygous form of HbS (HbSS).from one place instead of glutamine with valine in place 6 of the ye- globin chain.the cells also lead to polymerization and vaso-occlussion in the vasculature. Type β - globin is found inshort arm of chromosome 11. The combination of two tununts ant-globin subunits form hemoglobin S (HbS). Less -oxygen conditions, the absence of polar amino acids in the sixth ye-globin chain promotes diversityhemoglobin polymerization, which reverses red blood cells and then cuts and reduces their stiffness.
Article Details
Unique Paper ID: 152270 Publication Volume & Issue: Volume 8, Issue 2 Page(s): 871 - 873
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